Recommended SFRT Dose Metrics
GRID Therapy Dosimetry metrics
Target Volume Metrics
| Planning target volume (PTV, in cm3) |
| Output factor (OUTd ) at prescription depth (d) (in Gy/MU) |
Dose Metrics
| Prescription dose (Dp, in Gy) |
| Equivalent uniform dose (EUD, in Gy) |
| Dose covering 95% of target (D95, in Gy) |
| Dose covering 90% of target (D90, in Gy) |
| Dose covering 50% of target (D50, in Gy) |
| Dose covering 20% of target (D20, in Gy) |
| Dose covering 10% of target (D10, in Gy) |
| Dose covering 5% of target (D5, in Gy) |
| Valley/peak dose ratio at the tumor center depth (VPDR) |
| D10/D90, PVDR |
| Number of high dose cores (n) |
| High dose core number density (HDCN=n*100/GTV, cores per 100 cm3) |
Lattice Therapy Dosimetry metrics
Target Volume Metrics
| Gross target volume (GTV, in cm3) |
| Volume of Lattice, Vlattice |
| Volume of Vertices, Vvertices |
Dose Metrics
| Prescription dose (Dp, in Gy) |
| Equivalent uniform dose (EUD, in Gy) |
| Dose covering 95% of target (D95, in Gy) |
| Dose covering 90% of target (D90, in Gy) |
| Dose covering 50% of target (D50, in Gy) |
| Dose covering 20% of target (D20, in Gy) |
| Dose covering 10% of target (D10, in Gy) |
| Dose covering 5% of target (D5, in Gy) |
| D95/D5 |
| D10/D90, PVDR |
| Number of vertices, or high dose cores (n) |
| High dose core number density (HDCN=n*100/GTV, cores per 100 cm3) |
Reference:
Xiaodong Wu, et al, et al, Radiat Res 2020
Dec 1, 194 (6): 737-746
Hualin Zhang, et al, Radiat Res 2020 Dec 1,
194 (6): 665-677
