Zhang, et al · Cancers, 2022
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SFRT · GRID · Lattice Radiation Therapy
Spatially Fractionated Radiation Therapy
Spatially fractionated radiation therapy (SFRT) is a radiation therapy modality characterized by the delivery of high and intentionally heterogeneous dose using photon, electron or proton beams for the management of patients with bulky tumors. An ample body of literature has shown drastic and often rapid tumor responses to SFRT with unexpectedly low toxicity rates in the treatment of bulky, recurrent or therapy-refractory tumors.
A living repository of the SFRT literature for search, learning
and citation
Tools & Resources
Everything SFRT, in one place
Interactive tools and a curated library built for clinical physicists and radiation oncologists.
GRID EUD Calculator
Estimate the equivalent uniform dose (EUD) for GRID collimator-based SFRT across radiosensitive, semisensitive and radioresistant tumor classes, with a full dose profile.
Open the calculatorResearch Repository
A searchable, citable library of all relevant SFRT publications, organized by topic — from GRID and Lattice dosimetry to clinical outcomes.
Browse publicationsSFRT World
A global map showing where in the world SFRT practitioners and researchers have been using these resources.
View the world map
About This Site
A new modality, new challenges
A departure from convention
For clinical physicists and radiation oncologists, SFRT is a profound departure from the well-established dosimetric and planning principles, thus it poses new and unfamiliar challenges.
A repository for the community
This website houses a repository of all relevant SFRT publications for users' search, learning and citation — together with the dosimetric metrics and tools that support GRID and Lattice practice.
Key References
