Spatially Fractionated Radiation Therapy

Spatially fractionated radiation therapy (SFRT) is a radiation therapy modality characterized by the delivery of high and intentionally heterogeneous dose using photon, electron or proton beams for the management of patients with bulky tumors. An ample body of literature has shown drastic and often rapid tumor responses to SFRT with unexpectedly low toxicity rates in the treatment of bulky, recurrent or therapy-refractory tumors.

For clinical physicists and radiation oncologists, SFRT is a profound departure from the well-established dosimetric and planning principles, thus it poses new and unfamiliar challenges.

This website houses a repository of all relevant SFRT publications for users' search, learning and citation.